Chelsea have Pedro back from suspension as they bid for a record 14 consecutive wins in a single top-flight season.
Nemanja Matic was rested for the win over Stoke and could earn a recall.
Tottenham defenders Kyle Walker and Jan Vertonghen could return to the starting line-up after they missed the win over Watford through suspension.
Erik Lamela remains out with a hip problem but Mousa Dembele, who was rested against Watford, is expected to return in midfield.
John Murray: “Talk about rarity value. We might witness something here that no team has been able to achieve in any one top-flight season since this league was first played in 1888.
“And if they manage it, Chelsea will become only the fifth team to win 14 consecutive league matches at any time, in any of the divisions.
“Tottenham are already one of the victims of this Chelsea winning streak, having lost at Stamford Bridge in November. But they’ll have other ideas this time round, and with good reason too, after running into a rich vein of form of their own with four successive wins.”
Tottenham manager Mauricio Pochettino: “Chelsea arrive in very good shape – us too after the last few games.
“It will be a very tough game and a great opportunity for us to try to stop them and try to reduce the gap.
“It’s important, I think it’s important for us and for the Premier League to try to win and try to stop them and reduce the gap.”
Chelsea head coach Antonio Conte: “Now it’s not easy after 13 wins in a row you face teams that want to beat you not only to take three points, but for many reasons.
“It’s more difficult. We must know this.
“I think it’s very difficult to repeat this run. To win 16 games, draw one game and lose two games is a great achievement for us.”
Tottenham were impressive at Watford and they seem to have found a momentum now with Harry Kane and Dele Alli finding form.
I have a feeling they will halt the Chelsea surge which has been so impressive. To win 13 games in a row is just fantastic but Chelsea have some hard fixtures on the horizon.
SAM (Sports Analytics Machine) is a super-computer created by @ProfIanMcHale at the University of Salford that is used to predict the outcome of football matches.
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